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Sunil Paliwal

20022023

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  • Design and biological characterization of a series of dual mechanism ERK1/2 inhibitors with a Triazolopyridinone core

    Lotfaliansaremi, S., Cornwell, S., Casillas, C., Sabio, M., Tolias, P., Windsor, W. & Paliwal, S., Apr 2023, In: Chemical Biology and Drug Design. 101, 4, p. 837-847 11 p.

    Research output: Contribution to journal › Article › peer-review

  • Discovery of ZN-c3, a Highly Potent and Selective Wee1 Inhibitor Undergoing Evaluation in Clinical Trials for the Treatment of Cancer

    Huang, P. Q., Boren, B. C., Hegde, S. G., Liu, H., Unni, A. K., Abraham, S., Hopkins, C. D., Paliwal, S., Samatar, A. A., Li, J. & Bunker, K. D., 9 Sep 2021, In: Journal of Medicinal Chemistry. 64, 17, p. 13004-13024 21 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    56 Scopus citations

  • Discovery of 3(S)-thiomethyl pyrrolidine ERK inhibitors for oncology

    Boga, S. B., Alhassan, A. B., Cooper, A. B., Doll, R., Shih, N. Y., Shipps, G., Deng, Y., Zhu, H., Nan, Y., Sun, R., Zhu, L., Desai, J., Patel, M., Muppalla, K., Gao, X., Wang, J., Yao, X., Kelly, J., Gudipati, S. & Paliwal, S. & 16 others, Tsui, H. C., Wang, T., Sherborne, B., Xiao, L., Hruza, A., Buevich, A., Zhang, L. K., Hesk, D., Samatar, A. A., Carr, D., Long, B., Black, S., Dayananth, P., Windsor, W., Kirschmeier, P. & Bishop, R., 15 Jun 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 11, p. 2029-2034 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    15 Scopus citations

  • MK-8353: Discovery of an Orally Bioavailable Dual Mechanism ERK Inhibitor for Oncology

    Boga, S. B., Deng, Y., Zhu, L., Nan, Y., Cooper, A. B., Shipps, G. W., Doll, R., Shih, N. Y., Zhu, H., Sun, R., Wang, T., Paliwal, S., Tsui, H. C., Gao, X., Yao, X., Desai, J., Wang, J., Alhassan, A. B., Kelly, J. & Patel, M. & 21 others, Muppalla, K., Gudipati, S., Zhang, L. K., Buevich, A., Hesk, D., Carr, D., Dayananth, P., Black, S., Mei, H., Cox, K., Sherborne, B., Hruza, A. W., Xiao, L., Jin, W., Long, B., Liu, G., Taylor, S. A., Kirschmeier, P., Windsor, W. T., Bishop, R. & Samatar, A. A., 12 Jul 2018, In: ACS Medicinal Chemistry Letters. 9, 7, p. 761-767 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    52 Scopus citations

  • Potent and Selective Amidopyrazole Inhibitors of IRAK4 That Are Efficacious in a Rodent Model of Inflammation

    McElroy, W. T., Tan, Z., Ho, G., Paliwal, S., Li, G., Seganish, W. M., Tulshian, D., Tata, J., Fischmann, T. O., Sondey, C., Bian, H., Bober, L., Jackson, J., Garlisi, C. G., Devito, K., Fossetta, J., Lundell, D. & Niu, X., 11 Jun 2015, In: ACS Medicinal Chemistry Letters. 6, 6, p. 677-682 6 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    41 Scopus citations
View all 15 Research outputs