Abstract
A gold-catalyzed regioselective heteroannulation strategy has been developed for the concise and efficient synthesis of imidazo[1,2-a]pyrazinones. The protocol allows the introduction of diversity via the application of substituted propargyl amines or via Suzuki-coupling of the generated imidazo[1,2-a]pyrazinones with various (het)aryl boronic acids.
Original language | English |
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Pages (from-to) | 359-365 |
Number of pages | 7 |
Journal | Tetrahedron |
Volume | 69 |
Issue number | 1 |
DOIs | |
State | Published - 7 Jan 2013 |
Keywords
- Alkyne
- Gold
- Heteroannulation
- Imidazopyrazinone
- Suzuki