An unexpected ion-molecule adduct in negative-ion collision-induced decomposition ion-trap mass spectra of halogenated benzoic acids

Athula B. Attygalle, Najeh Kharbatia, Jason Bialecki, Josef Ruzicka, Aleš Svatoš, Einar J. Stauber

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

The ion observed at m/z 145 when product ion spectra of iodobenzoate anions are recorded using iontrap mass spectrometers corresponds to the adduct ion [I(H2O)-. The elements of water required for the formation of this adduct do not originate from the precursor ion but from traces of moisture present in the helium buffer gas. A collision-induced decomposition (CID) spectrum recorded from the [M-H]- ion (m/z 251) derived from 3-iodo[2,4,5,6-2H4]benzoic acid also showed an ion at m/z 145. This observation confirmed that the m/z 145 is not a product ion resulting from a direct neutral loss from the carboxylate anion. 79Bromobenzoate anions produce similar results showing an ion at m/z 97 for [79Br(H2O)]-. The ion-molecule reaction observed here is unique to ion-trap mass spectrometers since a corresponding ion was not observed under our experimental conditions in spectra recorded with in-space tandem mass spectrometers such as triple quadrupole or quadrupole time-of-flight instruments.

Original languageEnglish
Pages (from-to)2265-2270
Number of pages6
JournalRapid Communications in Mass Spectrometry
Volume20
Issue number15
DOIs
StatePublished - 2006

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