TY - JOUR
T1 - An unexpected ion-molecule adduct in negative-ion collision-induced decomposition ion-trap mass spectra of halogenated benzoic acids
AU - Attygalle, Athula B.
AU - Kharbatia, Najeh
AU - Bialecki, Jason
AU - Ruzicka, Josef
AU - Svatoš, Aleš
AU - Stauber, Einar J.
PY - 2006
Y1 - 2006
N2 - The ion observed at m/z 145 when product ion spectra of iodobenzoate anions are recorded using iontrap mass spectrometers corresponds to the adduct ion [I(H2O)-. The elements of water required for the formation of this adduct do not originate from the precursor ion but from traces of moisture present in the helium buffer gas. A collision-induced decomposition (CID) spectrum recorded from the [M-H]- ion (m/z 251) derived from 3-iodo[2,4,5,6-2H4]benzoic acid also showed an ion at m/z 145. This observation confirmed that the m/z 145 is not a product ion resulting from a direct neutral loss from the carboxylate anion. 79Bromobenzoate anions produce similar results showing an ion at m/z 97 for [79Br(H2O)]-. The ion-molecule reaction observed here is unique to ion-trap mass spectrometers since a corresponding ion was not observed under our experimental conditions in spectra recorded with in-space tandem mass spectrometers such as triple quadrupole or quadrupole time-of-flight instruments.
AB - The ion observed at m/z 145 when product ion spectra of iodobenzoate anions are recorded using iontrap mass spectrometers corresponds to the adduct ion [I(H2O)-. The elements of water required for the formation of this adduct do not originate from the precursor ion but from traces of moisture present in the helium buffer gas. A collision-induced decomposition (CID) spectrum recorded from the [M-H]- ion (m/z 251) derived from 3-iodo[2,4,5,6-2H4]benzoic acid also showed an ion at m/z 145. This observation confirmed that the m/z 145 is not a product ion resulting from a direct neutral loss from the carboxylate anion. 79Bromobenzoate anions produce similar results showing an ion at m/z 97 for [79Br(H2O)]-. The ion-molecule reaction observed here is unique to ion-trap mass spectrometers since a corresponding ion was not observed under our experimental conditions in spectra recorded with in-space tandem mass spectrometers such as triple quadrupole or quadrupole time-of-flight instruments.
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U2 - 10.1002/rcm.2582
DO - 10.1002/rcm.2582
M3 - Article
AN - SCOPUS:33746889063
SN - 0951-4198
VL - 20
SP - 2265
EP - 2270
JO - Rapid Communications in Mass Spectrometry
JF - Rapid Communications in Mass Spectrometry
IS - 15
ER -