Biointeractive hydrogels

Peter Krsko; Matthew Libera

doi:10.1016/S1369-7021(05)71223-2

Biointeractive hydrogels

Peter Krsko, Matthew Libera

Department of Chemical Engineering and Materials Science

Stevens Institute of Technology

Research output: Contribution to journal › Article › peer-review

105 Scopus citations

Abstract

Polyethelyne glycol(PEG), when present on a surface, decreases the adsorption of proteins and the adhesion of cells and exhibits structural, chemical and physical properties of extracellular matrix(ECM). It is used as a benchmark, against which many new antifouling materials are compared. PEG can form coatings which require the formation of hydrogels that are networks of macromolecules stabilized either by chemical or physical crosslinks and can swell extensively without getting dissolved. The crosslinking and swelling of PEG hydrogels are controlled by electron dose. Patterning of hydrogels requires combination of photolithographic methods with photopolymerization.

Original language	English
Pages (from-to)	36-44
Number of pages	9
Journal	Materials Today
Volume	8
Issue number	12
DOIs	https://doi.org/10.1016/S1369-7021(05)71223-2
State	Published - Dec 2005

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abstract = "Polyethelyne glycol(PEG), when present on a surface, decreases the adsorption of proteins and the adhesion of cells and exhibits structural, chemical and physical properties of extracellular matrix(ECM). It is used as a benchmark, against which many new antifouling materials are compared. PEG can form coatings which require the formation of hydrogels that are networks of macromolecules stabilized either by chemical or physical crosslinks and can swell extensively without getting dissolved. The crosslinking and swelling of PEG hydrogels are controlled by electron dose. Patterning of hydrogels requires combination of photolithographic methods with photopolymerization.",

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AB - Polyethelyne glycol(PEG), when present on a surface, decreases the adsorption of proteins and the adhesion of cells and exhibits structural, chemical and physical properties of extracellular matrix(ECM). It is used as a benchmark, against which many new antifouling materials are compared. PEG can form coatings which require the formation of hydrogels that are networks of macromolecules stabilized either by chemical or physical crosslinks and can swell extensively without getting dissolved. The crosslinking and swelling of PEG hydrogels are controlled by electron dose. Patterning of hydrogels requires combination of photolithographic methods with photopolymerization.

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Biointeractive hydrogels

Abstract

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