TY - JOUR
T1 - Biomedical application of immobilized enzymes
AU - Liang, Jun F.
AU - Li, Yong T.
AU - Yang, Victor C.
PY - 2000
Y1 - 2000
N2 - Reports on chemical immobilization of proteins and enzymes first appeared in the 1960s. Since then, immobilized proteins and enzymes have been widely used in the processing of variety of products and increasingly used in the field of medicine. Here, we present a review of recent developments in immobilized enzyme use in medicine. Generally speaking, the use of immobilized enzyme in medicine can be divided into two major categories: biosensors and bioreactors. A brief overview of the evolution of the biosensor and bioreactor technology, of currently existing applications of immobilized enzymes, of problems that researchers encountered, and of possible future developments will be presented. (C) 2000 Wiley-Liss, Inc.
AB - Reports on chemical immobilization of proteins and enzymes first appeared in the 1960s. Since then, immobilized proteins and enzymes have been widely used in the processing of variety of products and increasingly used in the field of medicine. Here, we present a review of recent developments in immobilized enzyme use in medicine. Generally speaking, the use of immobilized enzyme in medicine can be divided into two major categories: biosensors and bioreactors. A brief overview of the evolution of the biosensor and bioreactor technology, of currently existing applications of immobilized enzymes, of problems that researchers encountered, and of possible future developments will be presented. (C) 2000 Wiley-Liss, Inc.
KW - Bioreactor
KW - Biosensor
KW - Enzyme
KW - Immobilization
UR - http://www.scopus.com/inward/record.url?scp=0033818431&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0033818431&partnerID=8YFLogxK
U2 - 10.1002/1520-6017(200008)89:8<979::AID-JPS2>3.0.CO;2-H
DO - 10.1002/1520-6017(200008)89:8<979::AID-JPS2>3.0.CO;2-H
M3 - Article
C2 - 10906721
AN - SCOPUS:0033818431
SN - 0022-3549
VL - 89
SP - 979
EP - 990
JO - Journal of Pharmaceutical Sciences
JF - Journal of Pharmaceutical Sciences
IS - 8
ER -