Biomimetic nanofiber-enabled rapid creation of skin grafts

The utilization of nanofibers for skin wound repair holds great promise due to their morphological and dimensional similarity to the native extracellular matrix (ECM). Electrospinning, a high voltage-driven spinning technique, enables cost-effective fabrication of nanofibers from versatile materials. Many advances have been made to fabricate and characterize various nanofibers for wound repair and the generation of skin grafts. We have also been intensively working on the fabrication of various biomimetic nanofibers utilizing them for accelerating the formation of skin tissues. Along with a summary of up-to-date progress occurring in the field, extensive effort is made in this book chapter to particularly highlight the use of nanofibers for the rapid creation of tissue-engineered skin grafts, crucial to the treatment of extensive deep burns and other skin wounds.