TY - JOUR
T1 - Chirped-pulse adiabatic control in coherent anti-Stokes Raman scattering for imaging of biological structure and dynamics
AU - Malinovskaya, Svetlana A.
AU - Malinovsky, Vladimir S.
PY - 2007/3/15
Y1 - 2007/3/15
N2 - Two novel control methods based on adiabatic passage are proposed to be implemented in coherent anti Stokes Raman scattering (CARS) microscopy for noninvasive imaging of biological structure and dynamics. The first method provides optimal pulse-area control of the resonant vibrational transitions by using a pair of equally linear-chirped pulses. The second method, named the “roof” method, utilizes the chirp sign variation at the central time and gives robust adiabatic excitation of the resonant vibrational mode. Both methods are robust with respect to suppression of the off-resonant transitions. The methods allow one to achieve chemical sensitivity with high resolution and can be used to obtain CARS spectra of biological molecules with efficiently suppressed background.
AB - Two novel control methods based on adiabatic passage are proposed to be implemented in coherent anti Stokes Raman scattering (CARS) microscopy for noninvasive imaging of biological structure and dynamics. The first method provides optimal pulse-area control of the resonant vibrational transitions by using a pair of equally linear-chirped pulses. The second method, named the “roof” method, utilizes the chirp sign variation at the central time and gives robust adiabatic excitation of the resonant vibrational mode. Both methods are robust with respect to suppression of the off-resonant transitions. The methods allow one to achieve chemical sensitivity with high resolution and can be used to obtain CARS spectra of biological molecules with efficiently suppressed background.
UR - http://www.scopus.com/inward/record.url?scp=33847607576&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33847607576&partnerID=8YFLogxK
U2 - 10.1364/OL.32.000707
DO - 10.1364/OL.32.000707
M3 - Article
C2 - 17308609
AN - SCOPUS:33847607576
SN - 0146-9592
VL - 32
SP - 707
EP - 709
JO - Optics Letters
JF - Optics Letters
IS - 6
ER -