TY - JOUR
T1 - Co-enhancement of fluorescence and singlet oxygen generation by silica-coated gold nanorods core-shell nanoparticle
AU - Ke, Xuebin
AU - Wang, Dong
AU - Chen, Changqing
AU - Yang, Anqi
AU - Han, Yu
AU - Ren, Lei
AU - Li, Donghui
AU - Wang, Hongjun
N1 - Publisher Copyright:
© 2014, Ke et al.; licensee Springer.
PY - 2014/12/1
Y1 - 2014/12/1
N2 - Metal-enhanced fluorescence (MEF) as a newly recognized technology has been attracting considerable attention and is widely used in fluorescence-based technology. In this paper, we reported a novel distance-dependent MEF and metal-enhanced singlet oxygen generation phenomenon based on silica-coated gold nanorods (AuNRs@SiO2) core-shell structure with tetra-substituted carboxyl aluminum phthalocyanine (AlC4Pc) that serve as both fluorophore and photosensitizer. When the AlC4Pc was linked on the surface of AuNRs@SiO2, the fluorescence intensity and singlet oxygen productivity varied with the thickness difference of silica shell from 2.1 to 28.6 nm. The co-enhancement effect reached the maximum of 7-fold and 2.1-fold, respectively, when the separation distance was 10.6 nm. These unique characteristics make the prepared core-shell nanoparticles promising for MEF-based biological imaging and photodynamics therapy.
AB - Metal-enhanced fluorescence (MEF) as a newly recognized technology has been attracting considerable attention and is widely used in fluorescence-based technology. In this paper, we reported a novel distance-dependent MEF and metal-enhanced singlet oxygen generation phenomenon based on silica-coated gold nanorods (AuNRs@SiO2) core-shell structure with tetra-substituted carboxyl aluminum phthalocyanine (AlC4Pc) that serve as both fluorophore and photosensitizer. When the AlC4Pc was linked on the surface of AuNRs@SiO2, the fluorescence intensity and singlet oxygen productivity varied with the thickness difference of silica shell from 2.1 to 28.6 nm. The co-enhancement effect reached the maximum of 7-fold and 2.1-fold, respectively, when the separation distance was 10.6 nm. These unique characteristics make the prepared core-shell nanoparticles promising for MEF-based biological imaging and photodynamics therapy.
KW - Metal-enhanced fluorescence
KW - Metal-enhanced singlet oxygen generation
KW - Silica-coated gold nanorods
KW - Surface plasmon resonance
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U2 - 10.1186/1556-276X-9-666
DO - 10.1186/1556-276X-9-666
M3 - Article
AN - SCOPUS:84928407166
SN - 1931-7573
VL - 9
JO - Nanoscale Research Letters
JF - Nanoscale Research Letters
IS - 1
M1 - 666
ER -