@inproceedings{f3ff48e02fb142789a87c736fcb862a8,
title = "Co-focused ultrasound and optical coherence elastography system for the study of age-related changes of biomechanical properties of crystalline lens in rabbit eyes",
abstract = "In this study, we utilize a confocal ultrasound and phase-sensitive optical coherence elastography (OCE) system to assess age-related changes in biomechanical properties of the crystalline lens in intact rabbit eyes in situ. Lowamplitude elastic deformations, induced on the surface of the lens by localized acoustic radiation force, were measured using phase-sensitive OCT. The results demonstrate that the displacements induced in young rabbit lenses are significantly larger than those in the mature lenses. Temporal analyses of the elastic waves are also demonstrated significant difference between young and old lenses, indicating that the stiffness of lens increases with the age. These results demonstrate possibility of OCE for completely noninvasive analysis and quantification of lens biomechanical properties, which could be used in many clinical and basic science applications such as surgeries and studies on lens physiology and function.",
keywords = "acoustic radiation, biomechanical properties, crystalline lens, force, optical coherence elastography (OCE)",
author = "Chen Wu and Zhaolong Han and Shang Wang and Jiasong Li and Manmohan Singh and Liu, {Chih Hao} and Salavat Aglyamov and Stanislav Emelianov and Fabrice Manns and Larin, {Kirill V.}",
note = "Publisher Copyright: {\textcopyright} 2015 SPIE.; 25th Conference on Ophthalmic Technologies ; Conference date: 07-02-2015 Through 08-02-2015",
year = "2015",
doi = "10.1117/12.2079532",
language = "English",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
editor = "Arthur Ho and Fabrice Manns and Soderberg, {Per G.}",
booktitle = "Ophthalmic Technologies XXV",
}