TY - JOUR
T1 - Controlling epileptiform activity with organic electronic ion pumps
AU - Williamson, Adam
AU - Rivnay, Jonathan
AU - Kergoat, Loïg
AU - Jonsson, Amanda
AU - Inal, Sahika
AU - Uguz, Ilke
AU - Ferro, Marc
AU - Ivanov, Anton
AU - Sjöström, Theresia Arbring
AU - Simon, Daniel T.
AU - Berggren, Magnus
AU - Malliaras, George G.
AU - Bernard, Christophe
N1 - Publisher Copyright:
© 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
PY - 2015/5/1
Y1 - 2015/5/1
N2 - In treating epilepsy, the ideal solution is to act at a seizure's onset, but only in the affected regions of the brain. Here, an organic electronic ion pump is demonstrated, which directly delivers on-demand pure molecules to specific brain regions. State-of-the-art organic devices and classical pharmacology are combined to control pathological activity in vitro, and the results are verified with electrophysiological recordings.
AB - In treating epilepsy, the ideal solution is to act at a seizure's onset, but only in the affected regions of the brain. Here, an organic electronic ion pump is demonstrated, which directly delivers on-demand pure molecules to specific brain regions. State-of-the-art organic devices and classical pharmacology are combined to control pathological activity in vitro, and the results are verified with electrophysiological recordings.
KW - neuroengineering
KW - organic bioelectronics
KW - organic electronic ion pumps
KW - PEDOT:PSS
UR - http://www.scopus.com/inward/record.url?scp=84929579888&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84929579888&partnerID=8YFLogxK
U2 - 10.1002/adma.201500482
DO - 10.1002/adma.201500482
M3 - Article
C2 - 25866154
AN - SCOPUS:84929579888
SN - 0935-9648
VL - 27
SP - 3138
EP - 3144
JO - Advanced Materials
JF - Advanced Materials
IS - 20
ER -