Creation of vessel-like patches enabled by poly(caprolactone)/collagen/ elastin composite nanofibers

Xiaochuan Yang; Hongjun Wang

doi:10.1109/NEBC.2010.5458178

Creation of vessel-like patches enabled by poly(caprolactone)/collagen/ elastin composite nanofibers

Xiaochuan Yang, Hongjun Wang

Department of Biomedical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

It is critical to fabricate ideal scaffolds for tissue engineered vascular graft. Nanofibers composted with collagen, elastin and polycaprolactone (PCL) were prepared by electrospinning. The obtained composite fibers had an average diameter around 300-500 nm. Mouse smooth muscles cells and endothelial cells cultured on these composite fibrous meshes showed enhanced cell attachment and accelerated cell proliferation. Three-dimesional cell-scaffolds construct were fabricated using layer-by-layer electrospinning technique. Taken together, the electrospun PCL fibers containing collagen, elastin and PCL show a great potential in vascular tissue engineering.

Original language	English
Title of host publication	Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010
DOIs	https://doi.org/10.1109/NEBC.2010.5458178
State	Published - 2010
Event	36th Annual Northeast Bioengineering Conference, NEBEC 2010 - New York, NY, United States Duration: 26 Mar 2010 → 28 Mar 2010

Publication series

Name	Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010

Conference

Conference	36th Annual Northeast Bioengineering Conference, NEBEC 2010
Country/Territory	United States
City	New York, NY
Period	26/03/10 → 28/03/10

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10.1109/NEBC.2010.5458178

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Yang, X., & Wang, H. (2010). Creation of vessel-like patches enabled by poly(caprolactone)/collagen/ elastin composite nanofibers. In Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010 Article 5458178 (Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010). https://doi.org/10.1109/NEBC.2010.5458178

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title = "Creation of vessel-like patches enabled by poly(caprolactone)/collagen/ elastin composite nanofibers",

abstract = "It is critical to fabricate ideal scaffolds for tissue engineered vascular graft. Nanofibers composted with collagen, elastin and polycaprolactone (PCL) were prepared by electrospinning. The obtained composite fibers had an average diameter around 300-500 nm. Mouse smooth muscles cells and endothelial cells cultured on these composite fibrous meshes showed enhanced cell attachment and accelerated cell proliferation. Three-dimesional cell-scaffolds construct were fabricated using layer-by-layer electrospinning technique. Taken together, the electrospun PCL fibers containing collagen, elastin and PCL show a great potential in vascular tissue engineering.",

author = "Xiaochuan Yang and Hongjun Wang",

year = "2010",

doi = "10.1109/NEBC.2010.5458178",

language = "English",

isbn = "9781424468799",

series = "Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010",

booktitle = "Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010",

note = "36th Annual Northeast Bioengineering Conference, NEBEC 2010 ; Conference date: 26-03-2010 Through 28-03-2010",

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Yang, X & Wang, H 2010, Creation of vessel-like patches enabled by poly(caprolactone)/collagen/ elastin composite nanofibers. in Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010., 5458178, Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010, 36th Annual Northeast Bioengineering Conference, NEBEC 2010, New York, NY, United States, 26/03/10. https://doi.org/10.1109/NEBC.2010.5458178

Creation of vessel-like patches enabled by poly(caprolactone)/collagen/ elastin composite nanofibers. / Yang, Xiaochuan; Wang, Hongjun.
Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010. 2010. 5458178 (Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Yang, Xiaochuan

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N2 - It is critical to fabricate ideal scaffolds for tissue engineered vascular graft. Nanofibers composted with collagen, elastin and polycaprolactone (PCL) were prepared by electrospinning. The obtained composite fibers had an average diameter around 300-500 nm. Mouse smooth muscles cells and endothelial cells cultured on these composite fibrous meshes showed enhanced cell attachment and accelerated cell proliferation. Three-dimesional cell-scaffolds construct were fabricated using layer-by-layer electrospinning technique. Taken together, the electrospun PCL fibers containing collagen, elastin and PCL show a great potential in vascular tissue engineering.

AB - It is critical to fabricate ideal scaffolds for tissue engineered vascular graft. Nanofibers composted with collagen, elastin and polycaprolactone (PCL) were prepared by electrospinning. The obtained composite fibers had an average diameter around 300-500 nm. Mouse smooth muscles cells and endothelial cells cultured on these composite fibrous meshes showed enhanced cell attachment and accelerated cell proliferation. Three-dimesional cell-scaffolds construct were fabricated using layer-by-layer electrospinning technique. Taken together, the electrospun PCL fibers containing collagen, elastin and PCL show a great potential in vascular tissue engineering.

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BT - Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010

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Creation of vessel-like patches enabled by poly(caprolactone)/collagen/ elastin composite nanofibers

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