TY - GEN
T1 - Development of a uniaxial cyclic stretch apparatus for tissue engineering
AU - Pang, Qiming
AU - Zu, Jean W.
AU - Siu, Geoffrey M.
AU - Li, Ren Ke
PY - 2010
Y1 - 2010
N2 - A uniaxial cyclic stretch apparatus is designed and developed p for tissue engineering research. The biostretch apparatus employs non-contact electromagnetic force to uniaxial stretch a rectangular Gelfoam® or RTV silicon scaffold. A reliable controller is implemented to independently control four stretch parameters: strength, frequency, pattern, and duration of the stretch time. The non-contact driving force and the specially designed mounting tray allow researchers to use standard Petri p dishes and commercially available CO2 incubators to culture an engineered tissue patch with mechanical stimulus. The apparatus greatly simplifies the culture process over existing biostretch apparatuses. Further, unlike traditional uniaxial stretch apparatuses, which normally fix one side and stretch other side, the new biostretch apparatus can also apply uniaxial stretch from both ends simultaneously. Using the biostretch apparatus, the distribution of strain on the Gelfoam® and GE RTV 6166 silicon scaffold is quantitatively analyzed.
AB - A uniaxial cyclic stretch apparatus is designed and developed p for tissue engineering research. The biostretch apparatus employs non-contact electromagnetic force to uniaxial stretch a rectangular Gelfoam® or RTV silicon scaffold. A reliable controller is implemented to independently control four stretch parameters: strength, frequency, pattern, and duration of the stretch time. The non-contact driving force and the specially designed mounting tray allow researchers to use standard Petri p dishes and commercially available CO2 incubators to culture an engineered tissue patch with mechanical stimulus. The apparatus greatly simplifies the culture process over existing biostretch apparatuses. Further, unlike traditional uniaxial stretch apparatuses, which normally fix one side and stretch other side, the new biostretch apparatus can also apply uniaxial stretch from both ends simultaneously. Using the biostretch apparatus, the distribution of strain on the Gelfoam® and GE RTV 6166 silicon scaffold is quantitatively analyzed.
KW - Biostretch apparatus
KW - Scaffold
KW - Strain
UR - http://www.scopus.com/inward/record.url?scp=77953713618&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77953713618&partnerID=8YFLogxK
U2 - 10.1115/DETC2009-86217
DO - 10.1115/DETC2009-86217
M3 - Conference contribution
AN - SCOPUS:77953713618
SN - 9780791849002
T3 - Proceedings of the ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference 2009, DETC2009
SP - 53
EP - 59
BT - Proceedings of the ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference 2009, DETC2009
T2 - 2009 ASME International Design Engineering Technical Conferences and Computers and Information in Engineering Conference, DETC2009
Y2 - 30 August 2009 through 2 September 2009
ER -