Dynamics of gametes and embryos in the oviduct: what can in vivo imaging reveal?

Shang Wang, Irina V. Larina

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

Understanding the physiological dynamics of gametes and embryos in the fallopian tube (oviduct) has significant implications for managing reproductive disorders and improving assisted reproductive technologies. Recent advancements in imaging of the mouse oviduct in vivo uncovered fascinating dynamics of gametes and embryos in their native states. These new imaging approaches and observations are bringing exciting momentum to uncover the otherwise-hidden processes orchestrating fertilization and pregnancy. For mechanistic investigations, in vivo imaging in genetic mouse models enables dynamic phenotyping of gene functions in the reproductive process. Here, we review these imaging methods, discuss insights recently revealed by in vivo imaging, and comment on emerging directions, aiming to stimulate new in vivo studies of reproductive dynamics.

Original languageEnglish
Pages (from-to)R25-R37
JournalReproduction
Volume165
Issue number2
DOIs
StatePublished - Feb 2023

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