Engineering Approaches in Ovarian Cancer Cell Culture

Marcin Iwanicki, Tonja Pavlovic, Panteha Behboodi

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Determination of the frequency of somatic mutations, copy number variations, and the composition of single-nucleus transcriptomes in epithelial ovarian cancer (OC) biopsies have provided crucial information about the heterogeneity of cancer cell assemblies and their various tumor microenvironments (TMs). Translating this information into tumor biology for the discovery of new treatments could be accomplished by the engineering tissue culture models of OC within its TM.

Original languageEnglish
Title of host publicationCurrent Cancer Research
Pages231-253
Number of pages23
DOIs
StatePublished - 2023

Publication series

NameCurrent Cancer Research
ISSN (Print)2199-2584
ISSN (Electronic)2199-2592

Keywords

  • Biomaterial
  • Dissemination
  • Endometrium
  • Fallopian tubes
  • Mesothelium
  • Microfluidic
  • Organoid
  • Organotypic culture

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