Engineering Approaches in Ovarian Cancer Cell Culture

Marcin Iwanicki; Tonja Pavlovic; Panteha Behboodi

doi:10.1007/978-3-031-22802-5_8

Engineering Approaches in Ovarian Cancer Cell Culture

Marcin Iwanicki
, Tonja Pavlovic
, Panteha Behboodi

Stevens Institute of Technology

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Determination of the frequency of somatic mutations, copy number variations, and the composition of single-nucleus transcriptomes in epithelial ovarian cancer (OC) biopsies have provided crucial information about the heterogeneity of cancer cell assemblies and their various tumor microenvironments (TMs). Translating this information into tumor biology for the discovery of new treatments could be accomplished by the engineering tissue culture models of OC within its TM.

Original language	English
Title of host publication	Current Cancer Research
Pages	231-253
Number of pages	23
DOIs	https://doi.org/10.1007/978-3-031-22802-5_8
State	Published - 2023

Publication series

Name	Current Cancer Research
ISSN (Print)	2199-2584
ISSN (Electronic)	2199-2592

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Biomaterial
Dissemination
Endometrium
Fallopian tubes
Mesothelium
Microfluidic
Organoid
Organotypic culture

Access to Document

10.1007/978-3-031-22802-5_8

Cite this

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abstract = "Determination of the frequency of somatic mutations, copy number variations, and the composition of single-nucleus transcriptomes in epithelial ovarian cancer (OC) biopsies have provided crucial information about the heterogeneity of cancer cell assemblies and their various tumor microenvironments (TMs). Translating this information into tumor biology for the discovery of new treatments could be accomplished by the engineering tissue culture models of OC within its TM.",

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author = "Marcin Iwanicki and Tonja Pavlovic and Panteha Behboodi",

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AU - Pavlovic, Tonja

AU - Behboodi, Panteha

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AB - Determination of the frequency of somatic mutations, copy number variations, and the composition of single-nucleus transcriptomes in epithelial ovarian cancer (OC) biopsies have provided crucial information about the heterogeneity of cancer cell assemblies and their various tumor microenvironments (TMs). Translating this information into tumor biology for the discovery of new treatments could be accomplished by the engineering tissue culture models of OC within its TM.

KW - Biomaterial

KW - Dissemination

KW - Endometrium

KW - Fallopian tubes

KW - Mesothelium

KW - Microfluidic

KW - Organoid

KW - Organotypic culture

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UR - https://www.scopus.com/pages/publications/85153180543#tab=citedBy

U2 - 10.1007/978-3-031-22802-5_8

DO - 10.1007/978-3-031-22802-5_8

M3 - Chapter

AN - SCOPUS:85153180543

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SP - 231

EP - 253

BT - Current Cancer Research

ER -

Engineering Approaches in Ovarian Cancer Cell Culture

Abstract

Publication series

UN SDGs

Keywords

Access to Document

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