Enhanced generation of reactive oxygen species using gold nanoparticles conjugated with protoporphyrin IX

Maung Kyaw Khaing Oo, Maria Gomez, Hongjun Wang, Henry Du

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Reactive oxygen species (ROS) is a vital trigger for photodynamic therapy (PDT) of cancer. We report the production of elevated ROS using gold nanoparticles (GNP) (20-100 nm in diameter) conjugated with Protophorphyrin IX (PpIX). The amount of ROS formation increases with the size of the GNP due to enhanced el ectromagnetic field resulting from localized surface plasmonic resonance.

Original languageEnglish
Title of host publicationProceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010
Pages93-94
Number of pages2
DOIs
StatePublished - 2010
Event1st Global Congress on NanoEngineering for Medicine and Biology: Advancing Health Care through NanoEngineering and Computing, NEMB 2010 - Houston, TX, United States
Duration: 7 Feb 201010 Feb 2010

Publication series

NameProceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010

Conference

Conference1st Global Congress on NanoEngineering for Medicine and Biology: Advancing Health Care through NanoEngineering and Computing, NEMB 2010
Country/TerritoryUnited States
CityHouston, TX
Period7/02/1010/02/10

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