Evaluation of dermal fillers with noncontact optical coherence elastography

Manmohan Singh, Shang Wang, Richard W. Yee, Zhaolong Han, Salavat R. Aglyamov, Kirill V. Larin

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Over 2 million dermal filler procedures are performed each year in the USA alone, and this figure is only expected to increase as the aging population continues to grow. Dermal filler treatments can last from a few months to years depending on the type of filler and its placement. Although adverse reactions are rare, they can be quite severe due to ischemic events and filler migration. Previously, techniques such as ultrasound or magnetic resonance imaging have been used to evaluate the filler injections. However, these techniques are not practical for real-time filler injection guidance due to limitations such as the physical presence of the transducer. In this work, we propose the use of optical coherence tomography (OCT) for image-guided dermal filler injections due to the high spatial and temporal resolution of OCT. In addition, we utilize a noncontact optical coherence elastography (OCE) technique, to evaluate the efficacy of the dermal filler injection. A grid of air-pulse OCE measurements was taken, and the dynamic response of the skin to the air-pulse was translated to the Young's modulus and shear viscosity. Our results show that OCT was able to visualize the dermal filler injection process, and that OCE was able to localize the dermal filler injection sites. Combined with functional techniques such as optical microangiography, and recent advanced in OCT hardware, OCT may be able to provide real-time injection guidance in 3D by visualizing blood vessels to prevent ischemic events.

Original languageEnglish
Title of host publicationOptical Elastography and Tissue Biomechanics IV
EditorsDavid D. Sampson, Kirill V. Larin
ISBN (Electronic)9781510605756
DOIs
StatePublished - 2017
EventOptical Elastography and Tissue Biomechanics IV - San Francisco, United States
Duration: 28 Jan 201730 Jan 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10067
ISSN (Print)1605-7422

Conference

ConferenceOptical Elastography and Tissue Biomechanics IV
Country/TerritoryUnited States
CitySan Francisco
Period28/01/1730/01/17

Keywords

  • Dermal filler
  • Facial sculpting
  • Optical coherence elastography
  • Optical coherence tomography
  • Viscoelasticity

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