Exploring the multiphysics of the brain during development, aging, and in neurological diseases

Johannes Weickenmeier

Research output: Contribution to journalLetterpeer-review

2 Scopus citations

Abstract

The human brain remains an endless source of wonder and represents an intruiging scientific frontier. Multiphysics approaches naturally lend themselves to combine our extensive knowledge about the neurobiology of aging and diseases with mechanics to better capture the multiscale behavior of the brain. Our group uses experimental methods, medical image analysis, and constitutive modeling to develop better disease models with the long-term goal to improve diagnosis, treatment, and ultimately enable prevention of many prevalent age- and disease-related brain changes. In the present perspective, we outline on-going work related to neurodevelopment, aging, and neurodegenerative disease.

Original languageEnglish
Article number100068
JournalBrain Multiphysics
Volume4
DOIs
StatePublished - Jan 2023

Keywords

  • Brain aging
  • Longitudinal medical image registration
  • Mechanical testing
  • Multiphysics brainmechanics
  • Neurodegenerative disease

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