TY - GEN
T1 - Human scalp and brain blood flow SCOS sensitivities via superficial temporal artery occlusion
AU - Mahler, Simon
N1 - Publisher Copyright:
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.
PY - 2026/3/5
Y1 - 2026/3/5
N2 - We present a non-invasive, multi-channel speckle contrast optical spectroscopy (SCOS) system for simultaneously measuring scalp and brain blood flow. By using seven source-detector separation channels, our SCOS system targets different tissue depths to separate scalp and brain signals. To validate this depth sensitivity, we applied a temporary occlusion of the superficial temporal artery - affecting only the scalp - and observed significant reductions in scalp-sensitive channels, with minimal change in brain-sensitive channels. Results from 20 human subjects demonstrated the ability to distinguish scalp and brain blood dynamics. This approach is a first experimental evaluation of SCOS systems capabilities to non-invasively probe cerebral hemodynamics, with potential applications in stroke, brain injury, and neurological monitoring.
AB - We present a non-invasive, multi-channel speckle contrast optical spectroscopy (SCOS) system for simultaneously measuring scalp and brain blood flow. By using seven source-detector separation channels, our SCOS system targets different tissue depths to separate scalp and brain signals. To validate this depth sensitivity, we applied a temporary occlusion of the superficial temporal artery - affecting only the scalp - and observed significant reductions in scalp-sensitive channels, with minimal change in brain-sensitive channels. Results from 20 human subjects demonstrated the ability to distinguish scalp and brain blood dynamics. This approach is a first experimental evaluation of SCOS systems capabilities to non-invasively probe cerebral hemodynamics, with potential applications in stroke, brain injury, and neurological monitoring.
KW - biophotonics
KW - brain imaging
KW - cerebral blood flow
KW - laser imaging
KW - speckle contrast
KW - speckle contrast optical spectroscopy
UR - https://www.scopus.com/pages/publications/105035624141
UR - https://www.scopus.com/pages/publications/105035624141#tab=citedBy
U2 - 10.1117/12.3081342
DO - 10.1117/12.3081342
M3 - Conference contribution
AN - SCOPUS:105035624141
T3 - Proceedings of SPIE - The International Society for Optical Engineering
BT - Biomedical Light Scattering XVI
A2 - Wax, Adam
A2 - Backman, Vadim
T2 - 16th Biomedical Light Scattering
Y2 - 17 January 2026 through 18 January 2026
ER -