Hydride Attack on a Coordinated Ferric Nitrosyl: Experimental and DFT Evidence for the Formation of a Heme Model-HNO Derivative

Erwin G. Abucayon, Rahul L. Khade, Douglas R. Powell, Yong Zhang, George B. Richter-Addo

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

Heme-HNO species are crucial intermediates in several biological processes. To date, no well-defined Fe heme-HNO model compounds have been reported. Hydride attack on the cationic ferric [(OEP)Fe(NO)(5-MeIm)]OTf (OEP = octaethylporphyrinato dianion) generates an Fe-HNO product that has been characterized by IR and 1H NMR spectroscopy. Results of DFT calculations reveal a direct attack of the hydride on the N atom of the coordinated ferric nitrosyl.

Original languageEnglish
Pages (from-to)104-107
Number of pages4
JournalJournal of the American Chemical Society
Volume138
Issue number1
DOIs
StatePublished - 13 Jan 2016

Fingerprint

Dive into the research topics of 'Hydride Attack on a Coordinated Ferric Nitrosyl: Experimental and DFT Evidence for the Formation of a Heme Model-HNO Derivative'. Together they form a unique fingerprint.

Cite this