Abstract
We use electron-beam patterned functional microgels to integrate self-reporting molecular beacons, dielectric microlenses, and solid-phase and/or solution-phase nucleic acid amplification in a viral-detection microarray model. The detection limits for different combinations of these elements range from 10-10 M for direct target-beacon hybridization alone to 10-18 M when all elements are integrated simultaneously.
Original language | English |
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Pages (from-to) | 7528-7533 |
Number of pages | 6 |
Journal | Analyst |
Volume | 145 |
Issue number | 23 |
DOIs | |
State | Published - 7 Dec 2020 |