Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy

Yamin Yang, Yue Hu, Henry Du, Hongjun Wang

Research output: Contribution to journalArticlepeer-review

60 Scopus citations

Abstract

Gold nanoparticles (Au NPs) with opposite surface charge can form aggregates through electrostatic interaction and exhibit surface plasmon resonance (SPR) induced-localized electromagnetic (EM) field enhancement under light irradiation. Intracellular aggregation of Au NPs can further improve the therapeutic efficiency of Au NP-enhanced photodynamic therapy of cancer by promoting singlet oxygen generation.

Original languageEnglish
Pages (from-to)7287-7290
Number of pages4
JournalChemical Communications
Volume50
Issue number55
DOIs
StatePublished - 12 Jun 2014

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