Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy

Yamin Yang; Yue Hu; Henry Du; Hongjun Wang

doi:10.1039/c4cc02376e

Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy

Yamin Yang, Yue Hu, Henry Du, Hongjun Wang

Stevens Institute of Technology

Research output: Contribution to journal › Article › peer-review

62 Scopus citations

Abstract

Gold nanoparticles (Au NPs) with opposite surface charge can form aggregates through electrostatic interaction and exhibit surface plasmon resonance (SPR) induced-localized electromagnetic (EM) field enhancement under light irradiation. Intracellular aggregation of Au NPs can further improve the therapeutic efficiency of Au NP-enhanced photodynamic therapy of cancer by promoting singlet oxygen generation.

Original language	English
Pages (from-to)	7287-7290
Number of pages	4
Journal	Chemical Communications
Volume	50
Issue number	55
DOIs	https://doi.org/10.1039/c4cc02376e
State	Published - 12 Jun 2014

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title = "Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy",

abstract = "Gold nanoparticles (Au NPs) with opposite surface charge can form aggregates through electrostatic interaction and exhibit surface plasmon resonance (SPR) induced-localized electromagnetic (EM) field enhancement under light irradiation. Intracellular aggregation of Au NPs can further improve the therapeutic efficiency of Au NP-enhanced photodynamic therapy of cancer by promoting singlet oxygen generation.",

author = "Yamin Yang and Yue Hu and Henry Du and Hongjun Wang",

year = "2014",

month = jun,

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doi = "10.1039/c4cc02376e",

language = "English",

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T1 - Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy

AU - Yang, Yamin

AU - Hu, Yue

AU - Du, Henry

AU - Wang, Hongjun

PY - 2014/6/12

Y1 - 2014/6/12

N2 - Gold nanoparticles (Au NPs) with opposite surface charge can form aggregates through electrostatic interaction and exhibit surface plasmon resonance (SPR) induced-localized electromagnetic (EM) field enhancement under light irradiation. Intracellular aggregation of Au NPs can further improve the therapeutic efficiency of Au NP-enhanced photodynamic therapy of cancer by promoting singlet oxygen generation.

AB - Gold nanoparticles (Au NPs) with opposite surface charge can form aggregates through electrostatic interaction and exhibit surface plasmon resonance (SPR) induced-localized electromagnetic (EM) field enhancement under light irradiation. Intracellular aggregation of Au NPs can further improve the therapeutic efficiency of Au NP-enhanced photodynamic therapy of cancer by promoting singlet oxygen generation.

UR - https://www.scopus.com/pages/publications/84902438209

UR - https://www.scopus.com/inward/citedby.url?scp=84902438209&partnerID=8YFLogxK

U2 - 10.1039/c4cc02376e

DO - 10.1039/c4cc02376e

M3 - Article

C2 - 24871860

AN - SCOPUS:84902438209

SN - 1359-7345

VL - 50

SP - 7287

EP - 7290

JO - Chemical Communications

JF - Chemical Communications

IS - 55

ER -

Intracellular gold nanoparticle aggregation and their potential applications in photodynamic therapy

Abstract

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