TY - JOUR
T1 - Label-free detection of zinc oxide nanowire using a graphene wrapping method
AU - You, Juneseok
AU - Jang, Kuewhan
AU - Lee, Sangmyung
AU - Bang, Doyeon
AU - Haam, Seungjoo
AU - Choi, Chang Hwan
AU - Park, Jinsung
AU - Na, Sungsoo
N1 - Publisher Copyright:
© 2015 Elsevier B.V.
PY - 2015/6/5
Y1 - 2015/6/5
N2 - Zinc oxide nanowires (ZnO NWs) have been attempted to various applications, such as piezoelectric devices, energy harvesting devices, self-powered nanosensors, and biomedical devices. However, recent reports have shown the toxic effect of ZnO NWs. In this report, we described the detection of ZnO NWs, for the first time using reduced graphene oxide (RGO) wrapping method. By wrapping RGO to ZnO NW (RGO-ZnO NW), we are able to aggregate ZnO NWs and increase the sensing performance. The detection measurement is based on the resonance frequency shift derived from mass variation of RGO-ZnO NW adsorption on the DNA immobilized resonator. The resonator is able to detect ZnO NWs with detection limit of 100ngmL-1 which is 2 order below the fatal toxic concentration of ZnO NWs in Human Monocyte Macrophages (HMMs). Furthermore, the resonator is able to detect ZnO NWs in real tap water, showing the potential as ZnO NWs screening platform in real environmental aqua system.
AB - Zinc oxide nanowires (ZnO NWs) have been attempted to various applications, such as piezoelectric devices, energy harvesting devices, self-powered nanosensors, and biomedical devices. However, recent reports have shown the toxic effect of ZnO NWs. In this report, we described the detection of ZnO NWs, for the first time using reduced graphene oxide (RGO) wrapping method. By wrapping RGO to ZnO NW (RGO-ZnO NW), we are able to aggregate ZnO NWs and increase the sensing performance. The detection measurement is based on the resonance frequency shift derived from mass variation of RGO-ZnO NW adsorption on the DNA immobilized resonator. The resonator is able to detect ZnO NWs with detection limit of 100ngmL-1 which is 2 order below the fatal toxic concentration of ZnO NWs in Human Monocyte Macrophages (HMMs). Furthermore, the resonator is able to detect ZnO NWs in real tap water, showing the potential as ZnO NWs screening platform in real environmental aqua system.
KW - Bioelectronics
KW - Microelectromechanical systems
KW - Nanowires
KW - Sensors/biosensors
KW - Zinc oxide
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U2 - 10.1016/j.bios.2015.01.036
DO - 10.1016/j.bios.2015.01.036
M3 - Article
C2 - 25636019
AN - SCOPUS:84921738084
SN - 0956-5663
VL - 68
SP - 481
EP - 486
JO - Biosensors and Bioelectronics
JF - Biosensors and Bioelectronics
ER -