Light-directed migration of D. discoideum slugs in microchannels

J. Kim, H. Ennis, T. Nguyen, R. Kessin, M. Stojanovic, Q. Lin

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

This paper presents light-directed migration of multi-cellular microorganisms (slugs) of Dictyostelium discoideum in a microchip. The microchip consists of a microchamber and intersecting microchannels fabricated from agar to provide a moist environment necessary for slug survival. Slugs are driven to migrate in the geometric confinements of the microchannels under the stimulation of light, with the direction of migration determined by the position of an optical fiber that introduces light into the microchip. Experimental results demonstrate that this approach effectively allows controlled migration of slugs and has potential applications to biologically based microactuators.

Original languageEnglish
Title of host publication2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Pages322-325
Number of pages4
DOIs
StatePublished - 2011
Event2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 - Beijing, China
Duration: 5 Jun 20119 Jun 2011

Publication series

Name2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11

Conference

Conference2011 16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11
Country/TerritoryChina
CityBeijing
Period5/06/119/06/11

Keywords

  • Dictyostelium discoideum
  • microactuators
  • microchannels
  • phototaxis
  • slug

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