@inproceedings{9223ecf535c8434781dc412d4385a380,
title = "Microchannel for intraocular pressure relief and glaucoma treatment",
abstract = "In this paper the deisgn, modeling, fabrication, and testing of an PDMS microchannel intended as an ocular implant for the maintanance of healthy intraocular pressure (IOP) and treatment of glaucoma are described. The winding serpentine microchannel provides a minimally invasive pathway for fluid to travel from the anterior chamber to the exterior of the eye. Analytical modeling using a friction factor correlated to channel cross section and FEM simulations predicted a pressure drop across the device around 2 kPa at the typical eye fluid production rate of 2 μL/min. A mm-scale and various μm-scale prototypes were fabricated by pouring and curing PDMS onto Su-8 molds patterned by photolithography. The pressure difference across the channel, which was designed to have a pressure drop of 2 kPa, was measured to be 1.47 kPa.",
keywords = "Glaucoma, MEMS, Microchannel, PDMS",
author = "D. Barth and J. Heureaux and B. Pilapil and {Ponce De Leon}, P. and K. Zhao and Yang, {E. H.}",
year = "2011",
language = "English",
isbn = "9781439871393",
series = "Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011",
pages = "524--527",
booktitle = "Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011",
note = "Nanotechnology 2011: Electronics, Devices, Fabrication, MEMS, Fluidics and Computational - 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011 ; Conference date: 13-06-2011 Through 16-06-2011",
}