Microfluidic technologies for head and neck cancer: From single-cell analysis to tumor-on-a-chip

Yamin Yang, Hongjun Wang

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations

Abstract

Emerging microfluidic technologies involving miniaturization for high throughput and integration with various on-line detection modalities hold intriguing advantages for cancer diagnosis, tumor microenvironment modeling, and drug evaluation. This book chapter overviews recent advances in diagnosis and therapy for head and neck cancer using microfluidic-based techniques. The basic working principles and experimental results of key microfluidic platforms for head and neck cancer biomarker analysis, cancer cell detection at single-cell levels, and tumor-on-chip model reconstruction for therapeutic assessment and drug evaluation are introduced.

Original languageEnglish
Title of host publicationEarly Detection and Treatment of Head & Neck Cancers: Practical Applications and Techniques for Detection, Diagnosis, and Treatment
Pages43-62
Number of pages20
ISBN (Electronic)9783030698591
DOIs
StatePublished - 7 May 2021

Keywords

  • Drug screening
  • Lab-on-a-chip
  • Microfluidics
  • Single-cell analysis
  • Tumor-on-a-chip

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