TY - GEN
T1 - Noninvasive in vivo millimeter-wave measurements of glucose
T2 - 42nd International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2017
AU - Siegel, Peter H.
AU - Tang, Adrian
AU - Kim, Rod
AU - Virbila, Gabriel
AU - Chang, Frank
AU - Pikov, Victor
N1 - Publisher Copyright:
© 2017 IEEE.
PY - 2017/10/12
Y1 - 2017/10/12
N2 - We present initial data on noninvasive millimeter-wave tracking of glucose levels in human subjects. Measurements were made using three separate test systems, all giving similar results: (1) a K-band (WR42) rectangular waveguide clamp coupled to a direct detector to measure transmission magnitude through the upper ear between 15 and 25 GHz; (2) a K-band waveguide clamp connected to a vector network analyzer to measure magnitude and phase of transmitted power through the ear lobe; and (3) a Ka-band rectangular waveguide clamp operating from 26-36 GHz also recording complex transmission coefficients through the ear lobe. A novel compact CMOS heterodyne transceiver operating at 19-21 GHz was also tested, but failed to show sufficient antenna-to-antenna power coupling to produce useful results. Data was collected during a standard oral glucose tolerance test (OGTT) in one healthy volunteer and correlated with blood glucose measurements using a commercial glucometer. Preliminary results show good correlation between blood glucose measurements (invasive) and both magnitude and phase of millimeter-wave transmission (non-invasive) through the skin, and are in accordance with our earlier animal experiments conducted on anesthetized rats.
AB - We present initial data on noninvasive millimeter-wave tracking of glucose levels in human subjects. Measurements were made using three separate test systems, all giving similar results: (1) a K-band (WR42) rectangular waveguide clamp coupled to a direct detector to measure transmission magnitude through the upper ear between 15 and 25 GHz; (2) a K-band waveguide clamp connected to a vector network analyzer to measure magnitude and phase of transmitted power through the ear lobe; and (3) a Ka-band rectangular waveguide clamp operating from 26-36 GHz also recording complex transmission coefficients through the ear lobe. A novel compact CMOS heterodyne transceiver operating at 19-21 GHz was also tested, but failed to show sufficient antenna-to-antenna power coupling to produce useful results. Data was collected during a standard oral glucose tolerance test (OGTT) in one healthy volunteer and correlated with blood glucose measurements using a commercial glucometer. Preliminary results show good correlation between blood glucose measurements (invasive) and both magnitude and phase of millimeter-wave transmission (non-invasive) through the skin, and are in accordance with our earlier animal experiments conducted on anesthetized rats.
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U2 - 10.1109/IRMMW-THz.2017.8067035
DO - 10.1109/IRMMW-THz.2017.8067035
M3 - Conference contribution
AN - SCOPUS:85033710158
T3 - International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz
BT - 2017 42nd International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz 2017
Y2 - 27 August 2017 through 1 September 2017
ER -