Abstract
This Letter describes a versatile synthetic approach to prepare physovenine and physostigmine analogs. A series of analogs were synthesized and evaluated for cholinesterase inhibition activities, including human acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) from human serum.
Original language | English |
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Pages (from-to) | 3046-3049 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 57 |
Issue number | 27-28 |
DOIs | |
State | Published - 2016 |
Keywords
- AChE inhibitors
- Physovenine and physostigmine analogs
- Radical reactions