Optical coherence tomography for image-guided dermal filler injection and biomechanical evaluation

Manmohan Singh, Shang Wang, Richard W. Yee, Zhaolong Han, Salavat R. Aglyamov, Kirill V. Larin

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Dermal fillers are a very popular anti-ag ing treatment with estimated sales in the billions of dollars and millions of procedures performed. As the aging population continues to grow, these figures are only e xpected to increase. Dermal fillers have various compositions depending on their intended applicati on. Reactions to dermal fillers can be severe, such as ischemic events and filler migration to the eyes. Howe ver, these adverse reactions are rare. Nevertheless, the capability to perform imag e-guided filler injections would minimize th e risk of such reacti ons. In addition, the biomechanical properties of various fillers have been evalua ted, but there has been no investigation on the effects of filler on the biomechanical properties of skin. In this work, we utilize optical cohe rence tomography (OCT) for visualizing dermal filler injections with micrometer-scale sp atial resolution. In addition, we utilize noncontact optical coherence elastography (OCE) to quantify the changes in the biomechan ical properties of pig skin after the dermal filler injections. OCT was successfully able to visualize the dermal filler injecti on process, and OCE showed that the viscoelasticity of the pig skin was increased locally at the filler injection sites. OCT may be able to provide real-time image guidance in 3D, and when combined with functional OCT techniques such as optical microangiography, could be used to avoid blood vessels during the injection.

Original languageEnglish
Title of host publicationPhotonics in Dermatology and Plastic Surgery
EditorsHaishan Zeng, Bernard Choi
ISBN (Electronic)9781510605152
DOIs
StatePublished - 2017
EventPhotonics in Dermatology and Plastic Surgery - San Francisco, United States
Duration: 28 Jan 201729 Jan 2017

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10037
ISSN (Print)1605-7422

Conference

ConferencePhotonics in Dermatology and Plastic Surgery
Country/TerritoryUnited States
CitySan Francisco
Period28/01/1729/01/17

Keywords

  • Optical coherence elastography
  • dermal filler
  • facial sculpting
  • optical coherence tomography
  • viscoelasticity

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