Optical detection and monitoring of pigmented skin lesions

J. J. Stamnes, G. Ryzhikov, M. Biryulina, B. Hamre, L. Zhao, K. Stamnes

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

A method is presented for discriminating between malignant and benign pigmented skin lesions based on multispectral and multi-angle images. It is discussed how to retrieve maps of physiology properties and morphometric parameters from recorded images using a bio-optical model, radiative transfer calculations, and nonlinear inversion, and how to employ automated zooming to extract lesion and surrounding masks. Training and validation of a classification scheme for separation between benign and malignant tissue yielded sensitivity/specificity ranging from 97%/97% for application to a small dataset comprised of lesions not used for training and validation to 99%/93% for application to a larger dataset.

Original languageEnglish
Article number#285389
JournalBiomedical Optics Express
Volume8
Issue number6
DOIs
StatePublished - 1 Jun 2017

Keywords

  • Blood or tissue constituent monitoring
  • Medical and biological imaging
  • Optical diagnostics for medicine
  • Tissue characterization

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