TY - JOUR
T1 - Optical detection and monitoring of pigmented skin lesions
AU - Stamnes, J. J.
AU - Ryzhikov, G.
AU - Biryulina, M.
AU - Hamre, B.
AU - Zhao, L.
AU - Stamnes, K.
N1 - Publisher Copyright:
© 2017 Optical Society of America.
PY - 2017/6/1
Y1 - 2017/6/1
N2 - A method is presented for discriminating between malignant and benign pigmented skin lesions based on multispectral and multi-angle images. It is discussed how to retrieve maps of physiology properties and morphometric parameters from recorded images using a bio-optical model, radiative transfer calculations, and nonlinear inversion, and how to employ automated zooming to extract lesion and surrounding masks. Training and validation of a classification scheme for separation between benign and malignant tissue yielded sensitivity/specificity ranging from 97%/97% for application to a small dataset comprised of lesions not used for training and validation to 99%/93% for application to a larger dataset.
AB - A method is presented for discriminating between malignant and benign pigmented skin lesions based on multispectral and multi-angle images. It is discussed how to retrieve maps of physiology properties and morphometric parameters from recorded images using a bio-optical model, radiative transfer calculations, and nonlinear inversion, and how to employ automated zooming to extract lesion and surrounding masks. Training and validation of a classification scheme for separation between benign and malignant tissue yielded sensitivity/specificity ranging from 97%/97% for application to a small dataset comprised of lesions not used for training and validation to 99%/93% for application to a larger dataset.
KW - Blood or tissue constituent monitoring
KW - Medical and biological imaging
KW - Optical diagnostics for medicine
KW - Tissue characterization
UR - http://www.scopus.com/inward/record.url?scp=85020161005&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85020161005&partnerID=8YFLogxK
U2 - 10.1364/BOE.8.002946
DO - 10.1364/BOE.8.002946
M3 - Article
AN - SCOPUS:85020161005
VL - 8
JO - Biomedical Optics Express
JF - Biomedical Optics Express
IS - 6
M1 - #285389
ER -