Organ Printing

Robert C. Chang, Filippos Tourlomousis

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Organ printing encompasses bioadditive, digitally controlled manufacturing processes for layered, patterned deposition of complex 3D cell-bearing biological structures. This chapter discusses printing techniques that have evolved to process high-density biopolymer cell suspensions. A review of state-of-art technologies points to a need to address the competing requirements of manufacturing scalability with large-volume patterning for clinical translation with biological exigencies to present cells with an in vivo microscale niche. To instruct process design and development, computational models of printed micro-organ testbeds, in tandem with an integrated strategy of materials processing, process modeling, and metrology for benchmarking functional tissue, will be critical.

Original languageEnglish
Title of host publication3D Bioprinting and Nanotechnology in Tissue Engineering and Regenerative Medicine
Pages489-503
Number of pages15
ISBN (Electronic)9780128245521
DOIs
StatePublished - 1 Jan 2022

Keywords

  • Bioadditive manufacturing
  • Biofabrication
  • Computational modeling
  • Micro-organ
  • Microextrusion-based printing
  • Organ printing
  • Regenerative medicine
  • Tissue engineering
  • Tissue printing
  • Tissue-on-a-chip

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