@inproceedings{86a7e2165c864f8a9d1aee2f04a9e8ba,
title = "Quantitative 4D OCT imaging of tubular mouse embryonic heart reveals its localized pumping mechanism",
abstract = "We present an imaging-based quantitative approach for studying the localized pumping mechanism of the early tubular heart in live mouse embryos. The method relies on 4D (3D+time) imaging of cardiodynamics and hemodynamics of the embryonic heart using structural and Doppler optical coherence tomography (OCT). Our results from the mouse embryo at embryonic day 9.0 (E9.0) show an interesting relationship between the endocardial luminal areas and the localized volumetric blood flows, suggesting that a localized pressure gradient induced by the heart wall movement causes the variation of blood flows, including both the velocity magnitude and flow direction. Data provide new insights into the pumping mechanism of the mammalian tubular heart at the early developmental stage.",
author = "Shang Wang and Riana Syed and Larina, {Irina V.}",
note = "Publisher Copyright: {\textcopyright} COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.; Dynamics and Fluctuations in Biomedical Photonics XVII 2020 ; Conference date: 01-02-2020 Through 03-02-2020",
year = "2020",
doi = "10.1117/12.2553962",
language = "English",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
editor = "Tuchin, {Valery V.} and Tuchin, {Valery V.} and Leahy, {Martin J.} and Wang, {Ruikang K.}",
booktitle = "Dynamics and Fluctuations in Biomedical Photonics XVII",
}