Rapid fabrication of biomimetic nanofiber-enabled skin grafts

X. Fu, H. Wang

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations

Abstract

The utilization of nanofibers for skin wound repair holds great promise due to their morphological and dimensional similarity to the native extracellular matrix (ECM). Electrospinning, a high voltage-driven spinning technique, enables cost-effective fabrication of nanofibers from versatile materials. Numerous progresses have been made in fabricating and characterizing various nanofibers for wound repair and the generation of new skin grafts. We have also been intensively working on the fabrication of various biomimetic nanofibers and utilizing them for accelerating the formation of skin tissues. Along with a summary of up-to- date progress occurring in the field, this chapter particularly highlights the use of nanofibers for the rapid creation of tissue-engineered skin grafts, crucial to the treatment of extensive deep burns.

Original languageEnglish
Title of host publicationNanomedicine
Subtitle of host publicationTechnologies and Applications
Pages428-459
Number of pages32
DOIs
StatePublished - Oct 2012

Keywords

  • Biomimetic nanofibers
  • Bottom-up cell assembly
  • Extensive burn
  • Tissue-engineered skin grafts
  • Wound repair

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