TY - JOUR
T1 - Reaction Gas Chromatography without Solvent for Identification of Nanogram Quantities of Natural Products
AU - Attygalle, Athula B.
AU - Morgan, E. David
PY - 1983
Y1 - 1983
N2 - A method is described for trapping nanogram quantities of compounds or mixtures from a gas chromatography column with approximately 85% efficiency and reinjecting the sample on the same or a different column, with or without carrying out a reaction, and all without contamination with solvent. The method includes a solvent-free ozonolysis technique for determining the position of double bonds in alkenes by using 200 ng of sample, even when low molecular weight carbonyl compounds are produced. Characterization of carbonyl compounds by sodium borohydride reduction, hydrogenation of alkenes, and cleavage of epoxides by periodic acid at this scale, without the use of solvents, are also described.
AB - A method is described for trapping nanogram quantities of compounds or mixtures from a gas chromatography column with approximately 85% efficiency and reinjecting the sample on the same or a different column, with or without carrying out a reaction, and all without contamination with solvent. The method includes a solvent-free ozonolysis technique for determining the position of double bonds in alkenes by using 200 ng of sample, even when low molecular weight carbonyl compounds are produced. Characterization of carbonyl compounds by sodium borohydride reduction, hydrogenation of alkenes, and cleavage of epoxides by periodic acid at this scale, without the use of solvents, are also described.
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U2 - 10.1021/ac00259a043
DO - 10.1021/ac00259a043
M3 - Article
AN - SCOPUS:0020781718
SN - 0003-2700
VL - 55
SP - 1379
EP - 1384
JO - Analytical Chemistry
JF - Analytical Chemistry
IS - 8
ER -