Reconstruction from a flexible number of projections in cone-beam computed tomography via active shape models

Peter B. Noël, Jason J. Corso, Jinhui Xu, Kenneth R. Hoffmann, Sebastian Schafer, Alan M. Walczak

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

With a steady increase of CT interventions, population dose is increasing. Thus, new approaches must be developed to reduce the dose. In this paper, we present a means for rapid identification and reconstruction of objects of interest in reconstructed data. Active shape models are first trained on sets of data obtained from similar subjects. A reconstruction is performed using a limited number of views. As each view is added, the reconstruction is evaluated using the active shape models. Once the object of interest is identified, the volume of interest alone is reconstructed, saving reconstruction time. Note that the data outside of the objects of interest can be reconstructed using fewer views or lower resolution providing the context of the region of interest data. An additional feature of our algorithm is that a reliable segmentation of objects of interest is achieved from a limited set of projections. Evaluations were performed using simulations with Shepp-Logan phantoms and animal studies. In our evaluations, regions of interest are identified using about 33 projections on average. The overlap of the identified regions with the true regions of interest is approximately 91%. The identification of the region of interest requires about 1/5 of the time required for full reconstruction, the time for reconstruction of the region of interest is currently determined by the fraction of voxels in the region of interest (i.e, voxels in region of interest/voxels in full volume). The algorithm has several important clinical applications, e.g., rotational angiography, digital tomosynthesis mammography, and limited view computed tomography.

Original languageEnglish
Title of host publicationMedical Imaging 2009 - Image Processing
DOIs
StatePublished - 2009
EventMedical Imaging 2009 - Image Processing - Lake Buena Vista, FL, United States
Duration: 8 Feb 200910 Feb 2009

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7259
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2009 - Image Processing
Country/TerritoryUnited States
CityLake Buena Vista, FL
Period8/02/0910/02/09

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