TY - JOUR
T1 - Self-polymerization of dopamine in acidic environments without oxygen
AU - Chen, Tung Po
AU - Liu, Tianchi
AU - Su, Tsan Liang
AU - Liang, Junfeng
N1 - Publisher Copyright:
© 2017 American Chemical Society.
PY - 2017/6/13
Y1 - 2017/6/13
N2 - An alkaline environment and the presence of oxygen are essential requirements for dopamine polymerization. In this study, we are the first to demonstrate the self-polymerization of dopamine through plasma-activated water (PAW) under acidic environments (pH < 5.5). Resulting poly(dopamine) (PDA) was characterized using Nanosizer, SEM, FTIR, UV-vis, 1H NMR, and fluorescence spectrophotometers and proved to have similar physical and chemical properties to those polymerized under a basic condition, except that the PDA particles formed in PAW were more stable and hardly aggregated at varied pHs. The PAW polymerization method avoids alkaline solutions and the presence of oxygen and thus extends the applications of dopamine polymerization, particularly in biomedical and pharmaceutical sciences.
AB - An alkaline environment and the presence of oxygen are essential requirements for dopamine polymerization. In this study, we are the first to demonstrate the self-polymerization of dopamine through plasma-activated water (PAW) under acidic environments (pH < 5.5). Resulting poly(dopamine) (PDA) was characterized using Nanosizer, SEM, FTIR, UV-vis, 1H NMR, and fluorescence spectrophotometers and proved to have similar physical and chemical properties to those polymerized under a basic condition, except that the PDA particles formed in PAW were more stable and hardly aggregated at varied pHs. The PAW polymerization method avoids alkaline solutions and the presence of oxygen and thus extends the applications of dopamine polymerization, particularly in biomedical and pharmaceutical sciences.
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U2 - 10.1021/acs.langmuir.7b01127
DO - 10.1021/acs.langmuir.7b01127
M3 - Article
C2 - 28505456
AN - SCOPUS:85020738386
SN - 0743-7463
VL - 33
SP - 5863
EP - 5871
JO - Langmuir
JF - Langmuir
IS - 23
ER -