Synthesis of deuterium labeled polyunsaturated fatty acids

Aleš Svatoš, Athula B. Attygalle, Jerrold Meinwald

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Compounds containing carbon-carbon double bonds bearing cis deuterium atoms can be prepared conveniently by treating disubstituted acetylenes with bis(2-deuteriocyclohexyl)borane-B-D1 [DB(Cy)2] followed by reaction with CH3CO2D. As an example, the preparation of labeled linolenic acid is reported.

Original languageEnglish
Pages (from-to)9497-9500
Number of pages4
JournalTetrahedron Letters
Volume35
Issue number51
DOIs
StatePublished - 19 Dec 1994

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