TY - GEN
T1 - System-independent assessment of OCT axial resolution with a "bar chart" phantom
AU - Agrawal, Anant
AU - Chang, Robert
AU - Connors, Megan
AU - Stafford, Christopher
AU - Hwang, Jeeseong
AU - Pfefer, T. Joshua
PY - 2011
Y1 - 2011
N2 - We present a optical phantom approach for the characterization of OCT axial resolution and contrast via multilayered "bar charts." We explored two methods to fabricate these phantoms: the first is based on monolayers of light-scattering microspheres with an intervening layer of transparent silicone, and the second involves alternating layers of scattering-enhanced silicone and transparent silicone. Varying the diameter of the microspheres and the thickness of the silicone layers permits different spatial frequencies to be realized in the axial dimension of the phantoms. Because the phantom's dimensions are accurately known independent of the OCT system, no information about the system's spatial calibration is required. We quantified the degree to which the bars in each phantom could be resolved with OCT, which provides insights into the axial contrast transfer function. Initial testing of these phantoms on time-resolved and Fourier-domain OCT platforms indicated that our approach can provide accurate, system-independent estimates of resolution.
AB - We present a optical phantom approach for the characterization of OCT axial resolution and contrast via multilayered "bar charts." We explored two methods to fabricate these phantoms: the first is based on monolayers of light-scattering microspheres with an intervening layer of transparent silicone, and the second involves alternating layers of scattering-enhanced silicone and transparent silicone. Varying the diameter of the microspheres and the thickness of the silicone layers permits different spatial frequencies to be realized in the axial dimension of the phantoms. Because the phantom's dimensions are accurately known independent of the OCT system, no information about the system's spatial calibration is required. We quantified the degree to which the bars in each phantom could be resolved with OCT, which provides insights into the axial contrast transfer function. Initial testing of these phantoms on time-resolved and Fourier-domain OCT platforms indicated that our approach can provide accurate, system-independent estimates of resolution.
KW - Optical coherence tomography
KW - Phantoms
KW - Resolution
UR - http://www.scopus.com/inward/record.url?scp=79953018766&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79953018766&partnerID=8YFLogxK
U2 - 10.1117/12.880958
DO - 10.1117/12.880958
M3 - Conference contribution
AN - SCOPUS:79953018766
SN - 9780819484437
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Optical Diagnostics and Sensing XI
T2 - Optical Diagnostics and Sensing XI: Toward Point-of-Care Diagnostics; and Design and Performance Validation of Phantoms Used in Conjunction with Optical Measurement of Tissue III
Y2 - 22 January 2011 through 26 January 2011
ER -