TY - JOUR
T1 - The Design and Fabrication of Engineered Tubular Tissue Constructs Enabled by Electrohydrodynamic Fabrication Techniques
T2 - A Review
AU - Zhang, Fucheng
AU - Cao, Kai
AU - Zaeri, Ahmadreza
AU - Zgeib, Ralf
AU - Chang, Robert C.
N1 - Publisher Copyright:
© 2024 The Author(s). Macromolecular Materials and Engineering published by Wiley-VCH GmbH.
PY - 2024/9
Y1 - 2024/9
N2 - Electrohydrodynamic processes have emerged as promising methods for fabricating polymetric fiber-based artificial tubular tissues. Existing review articles focus on the biological applications and processing materials associated with electrohydrodynamic processes in artificial tubular constructs, while overlooking the design and fabrication of these constructs. To address this gap, this review article emphasizes the design and fabrication of tubular tissue constructs enabled by employing electrohydrodynamic processes. This article begins by presenting an overview of two electrohydrodynamic processes: solution electrospinning (SE) and melt electrowriting (MEW). It then delves into the control of the fiber diameter enabled by SE and MEW, offering insights into the manipulation of processing parameters to achieve desired fiber diameters. Additionally, the review highlights cutting-edge strategies for electrohydrodynamic processes to create tubular structures with customized microarchitectures. This includes fiber alignment control for SE and pore morphology design for MEW. Moreover, the review covers the creation of customized macroscale tubular geometries through collector geometry design. Lastly, a comprehensive survey is presented for designing multiphasic tubular structures specifically for electrohydrodynamic techniques or in tandem with other techniques. The objective of this review is to offer a thorough understanding of the design considerations and potential applications of tubular structures fabricated by electrohydrodynamic processes.
AB - Electrohydrodynamic processes have emerged as promising methods for fabricating polymetric fiber-based artificial tubular tissues. Existing review articles focus on the biological applications and processing materials associated with electrohydrodynamic processes in artificial tubular constructs, while overlooking the design and fabrication of these constructs. To address this gap, this review article emphasizes the design and fabrication of tubular tissue constructs enabled by employing electrohydrodynamic processes. This article begins by presenting an overview of two electrohydrodynamic processes: solution electrospinning (SE) and melt electrowriting (MEW). It then delves into the control of the fiber diameter enabled by SE and MEW, offering insights into the manipulation of processing parameters to achieve desired fiber diameters. Additionally, the review highlights cutting-edge strategies for electrohydrodynamic processes to create tubular structures with customized microarchitectures. This includes fiber alignment control for SE and pore morphology design for MEW. Moreover, the review covers the creation of customized macroscale tubular geometries through collector geometry design. Lastly, a comprehensive survey is presented for designing multiphasic tubular structures specifically for electrohydrodynamic techniques or in tandem with other techniques. The objective of this review is to offer a thorough understanding of the design considerations and potential applications of tubular structures fabricated by electrohydrodynamic processes.
KW - electrohydrodynamic processes
KW - melt electrowriting
KW - solution electrospinning
KW - tissue engineering
KW - tubular structures
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U2 - 10.1002/mame.202400095
DO - 10.1002/mame.202400095
M3 - Review article
AN - SCOPUS:85198974126
SN - 1438-7492
VL - 309
JO - Macromolecular Materials and Engineering
JF - Macromolecular Materials and Engineering
IS - 9
M1 - 2400095
ER -