Ultra-wideband millimeter-wave dielectric characteristics of freshly excised normal and malignant human skin tissues

Amir Mirbeik-Sabzevari, Robin Ashinoff, Negar Tavassolian

Research output: Contribution to journalArticlepeer-review

73 Scopus citations

Abstract

Millimeter waves have recently gained attention for the evaluation of skin lesions and the detection of skin tumors. Such evaluations heavily rely on the dielectric contrasts existing between normal and malignant skin tissues at millimeter-wave frequencies. However, current studies on the dielectric properties of normal and diseased skin tissues at these frequencies are limited and inconsistent. In this study, a comprehensive dielectric spectroscopy study is conducted for the first time to characterize the ultrawideband dielectric properties of freshly excised normal and malignant skin tissues obtained from skin cancer patients having undergone Mohs micrographic surgeries at Hackensack University Medical Center. Measurements are conducted using a precision slim-form open-ended coaxial probe in conjunction with a millimeter-wave vector network analyzer over the frequency range of 0.5-50 GHz. A one-pole Cole-Cole model is fitted to the complex permittivity dataset of each sample. Statistically considerable contrasts are observed between the dielectric properties of malignant and normal skin tissues over the ultra-wideband millimeter-wave frequency range considered.

Original languageEnglish
Article number2749371
Pages (from-to)1320-1329
Number of pages10
JournalIEEE Transactions on Biomedical Engineering
Volume65
Issue number6
DOIs
StatePublished - Jun 2018

Keywords

  • Contrast study
  • Dielectric measurements
  • Malignant skin tissue
  • Millimeter-wave measurements
  • Normal skin tissue
  • Skin cancer

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